What endogenous creatinine clearance rate is?

　　What endogenous creatinine clearance rate is?
　　Many people do not understand, endogenous creatinine clearance What does it mean?
　　Hospital Deputy Director Wang kidney treatment center for everyone to explain this question.
　　The so-called endogenous creatinine is actually a useless waste generated in our body, is a product of our muscle metabolism, need to be integrated into the blood, so that in the post along with the blood flow through the kidneys, through the kidneys filter, remove it from the separated from the blood, and then through the urine excreted from the body, while the clearance, means can be discharged in the kidneys per minute per milliliter of blood creatinine content, we can calculate through the following methods:
　　Before the test, the patient should be tested for three days without creatinine diet, limiting their access to the amount of protein, but also to stay away from strenuous exercise, so that the blood creatinine concentration reaches a stable level.
　　Within 24 hours prior to the test ban diuretics and other drugs, urine specimens from 24 hours, while maintaining the proper moisture intake, remember, you can not take coffee and tea drinks.
　　Accurate measurement of all urine V (ml). Creatinine in urine (U) and serum creatinine (P), the above V, U and P three parameters into the formula.
　　Ccr = U × V / P (ml / min)
　　V: urine volume per minute (ml / min) = all urine volume (ml) ÷ (24 × 60) min
　　U: urine creatinine, umol / L
　　P: serum creatinine, umol / L
　　Because each person's kidneys are not the same size, medicine | Education Network collected urination also vary per minute, for the elimination of individual differences in body surface area can be corrected:
　　Correction Ccr = U × V / P × 1.73 / A
　　A: patients tested actual body surface area (m2), A according to their height, weight or figure with estimates obtained DuBois formula:
　　1.73: European and American adult body surface area (m2)
　　Correction clearance theory than the actual clearance rate more accurately reflects the glomerular filtration rate, but because of the lack of standard reference values people's body surface area, and no method to accurately calculate the body surface area.
　　These are the endogenous creatinine clearance calculation method is usually only used when clinical medicine treatment. If you need to artificially low removal efficiency can be adjusted.

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