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Recent data suggest that proteinuria PRO for more than 1g / day in patients subjected to administration of adrenocorticotropic hormone every other day to improve proteinuria PRO beneficial. Performance IgA nephropathy patients rapidly progressive renal impairment clinical treatment rule with rapidly progressive glomerulonephritis, can methylprednisolone pulse therapy, cyclophosphamide and plasmapheresis were strengthening treatment. IgA deposition to have minimal change nephrotic proteinuria there may control PRO. Lower IgA concentration, fewer proteinuria PRO can use Tripterygium glycosides foot situation, using the process should pay attention to the relevant deputy effect.