Pathogenesis of acute and chronic renal failure are what? Kidney
specialists in our hospital, said impaired renal function can be divided into
two types, acute and chronic renal impairment with impaired renal function. And
I nephropathy hospital experts pointed out that the two impaired renal function
has a different cause the onset of the original reasons for the reason that in
the end the incidence of acute and chronic renal failure, has it? Hospital
kidney specialist on the etiology of acute and chronic renal failure analysis
and explanation is as follows:
First, the incidence of acute renal impairment reasons
Etiology of acute renal impairment can be divided into pre-renal, renal,
post-renal three.
Prerenal main reasons that cause a variety of reasons not foot the absolute
or relative blood volume, which results in severe renal ischemia, renal
perfusion without feet, glomerular filtration rate (detoxification capacity)
decreased, do not grasp the correct time would cause irreversible renal cell
necrosis. More common causes of cardiovascular disease, such as acute myocardial
infarction, heart imbalance, congestive heart recession, pericardial tamponade:
infectious diseases such as bacterial sepsis, meningitis, encephalitis, epidemic
hemorrhagic fever, toxic bacillary dysentery, acute hepatitis or hepatorenal
syndrome, acute suppurative gangrenous cholecystitis, acute pancreatitis, shock
lung: after hemorrhagic shock, such as gastrointestinal bleeding, trauma and
surgical bleeding, postpartum hemorrhage, bleeding ectopic pregnancy, placental
abruption, bleeding, etc.: drugs or serum allergic anaphylactic shock: shock
such as a large number of severe dehydration caused by vomiting, diarrhea,
paralytic ileus, transit, side shoots diabetes disease acidosis.
The main reason for acute renal tubular necrosis, the etiology of severe
dehydration, blood loss and prolonged shock, misuse vasoconstrictor-induced
ischemic acute tubular necrosis: a class of drugs such as sodium amide (big
celebration toxins, etc.), sweet poison leaven, contrast agents, low molecular
weight dextran auxiliary drunk and biological toxins (snake venom, drug
poisoning, fish bile poisoning) caused by toxic heavy metals and acute tubular
necrosis, blood group incompatibility, mechanical damage, severe acute
nephritis, bleeding heat and other acute hemolytic disease often produce large
amounts of hemoglobin, or crush syndrome generated a lot of myoglobin, or
multiple bone tumors Yi, oliguric renal comprehensive, sulfonamides and uric
acid kidney stones and other small tubular obstruction caused by acute tubular
necrosis. Primary glomerular diseases such as rapidly progressive
glomerulonephritis, severe acute nephritis, such as lupus nephritis secondary
nephritis, allergic purpura move nephritis, Goodpasture syndrome, acute
interstitial nephritis, hemolytic uremic creatinine comprehensive high Zheng,
renal vascular diseases such as renal artery infarction, renal vein thrombosis
0, malignant glomerular sclerosis can cause acute renal damage.
Post-renal causes of major mountain in the urethra and cause blockage. The
main reason there are stones, blood clots, tumor compression, error bar
bilateral ureteral, sulfonamides and uric acid end product, soluble protein
coagulation (seen in multiple myeloma) and so on.
Second, chronic renal impairment etiology
I explain kidney specialist hospital, triggering etiology of many chronic
renal impairment can be broadly divided into the following three categories:
Kidney disease: disease mainly affects the kidneys, and in the kidneys as
the main performance, such as various chronic glomerulonephritis, chronic
interstitial nephritis (including chronic pyelonephritis), kidney stones, renal
tuberculosis, hereditary nephritis, multiple bursitis, medullary cystic disease.
renal artery stenosis, renal tubular acidosis.
Lower urinary tract blockage: as benign prostatic hypertrophy, prostate
cancer, urethral stricture, neurogenic bladder, etc. hazy, hazy mainly for
bladder dysfunction, easy to secondary infection caused by impaired renal
function.
Systemic diseases and poisoning: often due to renal involvement resulting
in impaired renal function. Such as high blood pressure, kidney
arteriosclerosis, malignant high blood pressure, the heart of the recession,
diabetes, gout, hyperkalemia or hypokalemia, primary and secondary amyloidosis,
nodular pieces nodosa, systemic lupus erythematosus , allergic purpura, bell
myeloma, macroglobulinemia, cirrhosis, analgesics and heavy metal poisoning.
It can be seen that unite the etiology can cause chronic renal impairment.
Thus active treatment of the primary disease, for away or delay the arrival of
chronic renal failure is extremely focused. Also look for them in the clinic is
also a look into the pathogenesis of some patients with chronic renal failure on
the show, its causes illness record is unclear, after various physical and
chemical examination is also difficult to determine, for this situation. Was
able to think of chronic nephritis occult through the development of chronic
renal failure and perhaps of greater.
The above is a kidney specialist hospital to this explanation, I believe
you all know, the pathogenesis of impaired renal function, there are many kinds,
I hope we can be vigilant in life, prevention of disease. I remind kidney
specialist hospital patients with impaired renal function, understanding of
their etiology contribute to a better treatment of disease. If you want to know
more knowledge of impaired renal function, please free to consult our hospital
nephrologist, a kidney specialist to have a professional analysis to explain to
you, contact Viber / Whatsapp: +8615131171391 Skype: kidneycarescommunity.